If you are running Ubuntu 11.04 with Playonlinux version 4.11  and recently updated Ubuntu, specifically :

• python-wxversion to version 2.8.11.0-0ubuntu8.1(natty-updates)
• python-wxgtk2.8 to version 2.8.11.0-0ubuntu8.1(natty-updates) 

you may have nun-functional Playonlinux apps on your desktop. Like I did.

To fix this problem just rollback to previous working version of these two packages i.e the 2.8.11.0-0ubuntu8 (natty).

To downgrade go to synaptic package manager click the package and then  click CTRL-E to force the previous version for both packages.

 

Another fine example of newer doesn't always better.

 

keyword : playonlinux error don't won't start fix wxwidget