If you have many Windows applications running under Wine, good chance are you'll need multiple versions of Wine. I only use two Win-apps, even they need two versions of Wine.
You can wait for the day when one-fits-all-version Wine to arrive, but until that day comes like it or not we must use multiple versions of Wine. So how to have different Wine for different Win-applications in your Ubuntu?

1. install PlayOnLinux, I use Karmic Koala and PlayOnLinux is already listed in Synaptic Package Manager, so go there and install it.
2. Tools -> Manage Wine Version -- Wine Versions tab; you can download and install different versions of Wine you need.
   
   
3. After that, install Windows applications you need, you can either download the apps from PlayOnLinux repository or manually install from installation file by clicking install a.pol package or an unsupported application and follow the steps.
   
   
4. after Windows application installations,  you can manage which Wine version to run which application on Tools -> Manage Wine Versions -- My Applications tab. Click the application and choose the Wine version on the drop box below it.
   
    
5. you can select what application to run on PlayOnLinux main window.
   
   

Enjoy.



keyword : multiple Wine versions